The Writers’ Forensic Community

Welcome to The Writers’ Forensic Community, a place where fiction writers can ask questions, make comments, and exchange ideas about all things medical or forensic. The hope is that we writers can learn from each other and at the same time give a nudge to our curiosity and creativity.

To submit a question or comment, go here.


6-23-07: Cleaning the Crime Scene

Q:            In my story, a serial killer murders young women in their apartments/homes.  Since these are violent deaths, and the victims fight back, there is ample chance for DNA to be left at the scene.  My question is what substance, or combination of substances, easily accessible by the general public (perhaps bought on-line) could be used to "clean up" the crime scene and make the job difficult or impossible for the police, in regards to the DNA evidence?
Sherri Painter, Georgia

A:            If either blood or semen is left at the scene then bleach would work. Any chlorine-bleach-containing cleaning substance can destroy DNA or at least damage it to the point of being unusable for identification. And these a readily available at your local supermarket. Criminals are using this more and more as they learn about it from CSI and Court TV.
            But—there’s always a but---blood is a liquid and seeps into all sorts of places. It can soak beneath floorboards and baseboards, between tiles and into grout, and deep into carpet pads. Here, simply lifting the floorboards or removing the baseboards or unseating the tiles or peeling back the carpet might reveal undamaged blood.
            Blood can also spatter on to walls and furniture and other objects. A careful search of the scene can often reveal tiny blood droplets that escaped the killer’s cleaning efforts. Blood can be unknowingly tracked or dripped from a small wound by the killer to areas that aren’t cleaned. The best place to find this type of evidence is near the corpse and along the killer’s escape route.
            And blood and semen can be found on the victim or her clothing or on the bed sheets or floor. These might also escape the killer’s view, particularly in nighttime attacks.

6-21-07: Versed Effects

Q:            I am working on a novel in which my main character is injected with Versed, then wakes up a few hours later with no memory of what happened. She goes to the hospital shortly afterwards. Would the hospital be able to detect Versed in her system? What would the side effects of the drug be once she woke up? Would she be drowsy, or would she feel normal? Does Versed cause permanent amnesia, or would it be possible for her to remember what happened after a few days? 
Cynthia Lynn Combs, Chula Vista, CA

A:            Versed (which is commonly used is pre-op and pre-procedure anesthesia) and several of the date rape drugs—GHB, Ecstasy, Ketamine, and Rohypnol share the effect of interfering with memory formation. While under the influence of these drugs the victim may seem awake and alert, or slightly giddy or sleepy—it varies from person to person, and will talk appropriately and answer questions and to observes appear more or less normal. That’s what makes these drugs so dangerous in a date rape situation. The victim will have absolutely no memory—or if any a very spotty memory---for events while under the drug’s influence. This loss of memory is permanent.
            The person is not sleepy or groggy or confused as with narcotics and sedatives, and they will suddenly return to real time but remember nothing for the previous few hours. It’s as if the drug turns off the movie and then it restarts suddenly when the drug’s effects dissipate. The victim would feel normal with little if any residual effects of the drug.
            When she went to the ER and told her story, drugs and particularly sedatives or one of the date rape drugs would be suspected and a toxicology evaluation would be done. The Versed would be found.

6-18-07: Corpse in Wood Chipper

Q:            I have a situation where the victim's body has been put through a wood chipper, and the remains are found in a plastic container. How would a medical examiner proceed to examine these remains, and what language would s/he use to describe them to an investigating officer? How would the process differ from a more conventional autopsy?
CM, Hinesburg, VT

A:            There is no particular terminology to define the mass that would remain. The ME would simply say the corpse was ground into pulp. There would be no limbs or organs, or much of anything. There would be no real autopsy since there is nothing to dissect. The ME would of course be able to determine blood type, DNA profile, and could do toxicological testing on the tissues, which might reveal any toxins present. He would also look for intact teeth in the hopes that these might help identify the remains if the identity wasn’t already known.
            Lastly he would search for any bullet fragments or perhaps the tip of a knife as finding either of these might point to the cause of death. If neither these nor toxins were found, the ME would be hard pressed to state what the cause of death was in this situation.

6-5-07: GSW to Abdomen

Q:            I'm writing a story about a character who is recovering from being shot twice in the abdomen.  If it's realistic recovery-wise, I'd like for one bullet to hit her spleen and the other to not damage any major organs, but to tear through some abdominal muscles. And my primary question has to do with advice for the medical timeline.  How long would be medically accurate or advisable for the following:
1--Time between being shot and arriving at the hospital
2--Time in surgery
3--Symptoms in various stages - about how long would she be in severe pain and sedated vs. moderate pain and lessening gradually to no pain whatsoever?
4--Days before she's released from hospital, assuming she has a minor post-surgery infection.
5--How long before she could lift an eight-month-old infant?
6--Would this type of injury require physical therapy and if so, what type of exercises? 
7--And regarding the minor infection, what would be the symptoms - fever, nausea, and listlessness?
Keri, Red Deer, Alberta, Canada

A:            The sooner the victim gets to the hospital the better but people survive abdominal gunshot wounds (GSWs) for many hours and even days. How rapidly the victim gets to the ER depends upon the location of the incident. If in a populated area of a big city the medics could have her in the ER in a matter of minutes. If in a rural or remote area, it could take hours.
            The surgery would be to remove the spleen (these are almost always removed when damaged and only rarely repaired since we get along fine without a spleen and this organ is difficult to repair) and to repair the damaged muscles and to clean any blood from the abdomen. It could take anywhere from an hour to 3 hours depending upon the surgeon and the exact nature of the injuries.
            The initial GSW would be very painful as would the trip to the hospital. The victim would of course be asleep during surgery and afterwards would have fairly typical post-operative pain. The pain would be significant the first 2 or 3 days and then gradually decline. By a week, she would be much better, but still uncomfortable. It would take about 3 or 4 weeks for the pain to resolve completely.
            Also, she would continually lose blood during the time between the GSW and the operation. As she lost blood her blood pressure 9BP) would gradually decline and she would slip into shock. During this time period she could also experience and combination and severity of these symptoms: nausea, shortness of breath, chills, dizziness, confusion, disorientation, sleepiness, and finally coma and if not treated death.
            A post-op infection is a serious problem and would prolong her hospitalization. It is impossible to say exactly how long since these infections come in a thousand flavors. With no infection and with all going well, she could be out of the hospital in as little as 4 or 5 days. With an infection, depending upon its severity and response to treatment, her hospitalization could be anywhere from a week to several months. It’s up to you.
            If all went well, she should be able to lift the child after a couple of weeks. Maybe with a bit of discomfort, but she could do it.
            She would really have physical therapy for this. Only get out f bed as soon as possible after surgery and gradually become wore mobile with progressive walking.

6-2-07: Skeletal Remains and Cause of Death

Q:            In my novel the body of a six-year-old boy is found entombed in a brick wall. The body has been there for 25 years and is mummified. These are my questions: How would the coroner go about establishing the cause of death? Could an autopsy be done on a body in that condition and would it be useful? Would there be a coroner's inquest in this case and, if so, who would attend?
M. Heath, Birmingham, AL

Q:            Skeletal remains present difficult problems for the ME. With no tissues to work with, the analysis of things such as gunshot wounds (GSWs), knife wounds, most illnesses, and any reliable toxicological testing is essentially impossible. But, not always. A bullet might punch a hole in the skull, fracture a rib, or damage another boney structure in a manner that the ME could deduce that a bullet must have cause the skeletal defect. Also, the bullet or some of its fragments might be found in or near the burial site or even imbedded in a bone. Same can be said for a knife blade. Certain boney cuts and scrapes might suggest that a blade was involved. And the tip or a small piece of the knife blade or an ice pick might be knocked loose during the attack and be found with the skeletal bones.
            Blunt trauma might also leave behind skeletal evidence. Hammers, crowbars, baseball bats, and other unusual implements can also leave behind boney defects that can be matched to one of these instruments and the ME might be able to guess that the weapon was one of these. For example, a circular defect in the skull would suggest a hammer while a wide, linear defect might suggest a baseball bat. An axe or hatchet could make deep cuts into the bones and even cut some in half.
            But finding such skeletal damage doesn’t necessarily mean that the injury was the cause of death. What if the person had broken a arm or suffered a skull fracture and survived it and was then killed or died from some other cause? Fractured bones heal in time. This healing is by way of callus (scar) formation at the area of injury and this process takes months to complete. And of course, no healing occurs after death. So, a fracture with a robust callus must have occurred months before death. On the other hand, peri-mortem (around the time of death) fractures show no signs of healing and thus no callus formation. Thus, a skull fracture that showed no signs of healing could have occurred around the time of death and may indeed be related to the cause of death. This means that a blow to the head or a fall could have led to the individual’s death. Conversely, well-healed fractures could not be directly related to the cause of death.
            But, what of fractures that occur years after death, after the skeleton has been exposed to nature for a considerable time period? Bones left in nature tend to undergo trauma from natural forces and from predators. Can the examiner determine when the fractures occurred? Often, he can.
            Living bones possess moisture, living protein, and fat, which makes them less brittle. Fractures tend to be spiral or “greenstick” in nature. Bones that have dessicated (dried out) are very brittle and tend to crumble more readily and fracture cleanly, usually parallel or at a cross-section to the long axis of the bone. By examining the nature of any fractures the forensic anthropologist may be able to distinguish pre-mortem from distant post-mortem fractures.
            So, based on the timing and nature of skeletal injuries, the forensic anthropologist and the ME might be able to determine the cause of death and whether it was self-inflicted, accidental, or homicidal in nature. Determining the manner of death is not always easy or accurate. What if the findings suggest that the individual died as a result of a skull fracture? Was this from a blow to the head (homicidal), a fall (accidental), or a fall after a heart attack or stroke (natural)?
    It’s not always easy.
    This skeletal examination by the ME and the forensic anthropologist would be the autopsy.
    The coroner could call for an inquest or not. It’s up to him and the courts. If so, the ME and any other scientist he designated, the DA, and the investigating officers would attend. It could be open to the public or closed at the coroner’s and the court’s discretion. If an arrest has been made, the suspect might also attend with his attorney. You might check with local law enforcement or with a local ju8deg to see how things are done in Birmingham to be sure.

5-26-07: GSW Infection

Q:            My character has been shot in the shoulder and two days after the surgery has developed an infection and high fever. Would he be taken back to the ICU for treatment (which I assume would be IV antibiotics)? Or would he be treated in his regular, private room? Also, is this infection scenario credible, and if so how quickly could he recover from it?
M.H., Maryland

A:            Wound infections are common complications of all types of wounds including gunshot wounds (GSWs). Treatment is indeed with IV antibiotics and keeping the wound clean and freshly dressed. The wound would be cleaned with Betadine—an antiseptic solution that is rusty red in color and with a very astringent odor—and a fresh dressing would be placed twice each day. It is also possible that the victim would have to return to surgery to debride the wound---this is the surgical removal of dead and infected tissue. At that time a drain might be placed to allow tissue fluids and blood (good media for bacterial growth) to drain away. This is simply a soft rubber tube that is placed within the wound to serve as a conduit to remove these fluids. It is usually left in pace for 2 or 3 days and then as the wound begins to heal it is simply tugged out.
            The victim might or might not be placed in the ICU, depending upon how ill he was. Most often these kinds of things can be handled on the surgical ward, but if he became very ill with high fevers and unstable blood pressures, he would go to the ICU until he stabilized.
            He could recover form the infection in a few days though it would take several weeks for the wound to heal properly. This is highly variable and depends upon the nature of the wound, the severity of the infection, the adequacy of the treatment, the healing ability of the victim, and luck. In general, if all went we might be in the hospital for the first week and then treated as an outpatient with antibiotics orally for the next couple of weeks.

5-25-07: Bruise Patterns

Q:            In a new book, my heroine is framed for murder, which involves a beating through martial arts technique and then a fatal push. Are there specifics that help authorities determine from (I assume) fatal injuries that can determine whether someone was pushed versus they fell?
            A mildly clever notion I had for clearing my heroine is for her to voluntarily have casts done of her knuckles. Having trained in karate in the past myself, I know that over time, your knuckles somewhat morph from hitting equipment, etc. So it occurs to me that bruising by knuckles on a body could be compared, or am I way off and the notion ludicrous? I.e. size of bruising from say a foot compared to a suspect's foot or hand?
Jeff Pearce, Toronto, ON, Canada

A:            Pushing almost never leaves any bruises in and of itself so distinguishing a push from and accidental fall is virtually impossible. The ME might be able to determine whether the bruises and injuries on the victim resulted from a fall or a series of blows with hands or other objects. Rocks and other objects can leave bruises just as hands and bats do and the ME might be able to discern a distinctive pattern that would distinguish exactly what made the bruises. Or not. It can go either way.
            Bruises do often reveal the pattern of the object that made the bruise. For example, a rope of a chain used for strangulation can leave behind neck bruises that reveal the braid or link pattern. A blow from a baseball bat or a flat board would leave different bruising patterns---the bat a narrower bruise with diffuse edges and the board a wider bruise with sharper edges. Bite marks often leave bruises that reflect the teeth pattern of the biter and these can sometimes be used to match to a dental impression made from a suspect.
            And knuckle bruises can sometimes be matched. Knuckles could leave a row of 2 to 4 more or less round bruises. The size and spacing could be used to rule out certain hands as having delivered the blow while leaving those of a similar size and spacing in the suspect list. The same could be true for the edge of the hand or foot. Either could leave a linear bruise that reflected the thickness of the side of the hand or foot. This would be less clear than would be the knuckles.
            Also, if the attacker wore a ring with an initial or other distinctive pattern, this pattern could be left as a bruise on the flesh of the victim and it is possible that it could be matched to the ring.
             So, the size and spacing of the knuckle bruises on the victim could eliminate or not eliminate your character as a suspect. It’s up to you. Whatever fits your plot needs will work.

5-17-07: Dwarfism and Giganticism in the Same Family

Q:            Could a family with a history of occasional dwarfism in its male children also have an occasional "giant" male child? My story takes place circa 1890.  Am I correct in assuming that treatments based on sheep pituitary glands would not have been 100 percent effective at reversing dwarfism at that time?
John Mullen, Poway, CA

A:            There are many causes of short stature---over 200 different varieties. True dwarfism is a genetic disorder. By far the most common is termed Achondroplastic Dwarfism, which is caused by a spontaneous mutation. This means that it isn’t necessarily passed on from parent to child and the parent doesn’t have to have the dwarf gene for the child to be a dwarf. Rather the defect occurs spontaneously and unpredictably.  Any conception can have this mutation so that normal parents can have a dwarf child. The mutation is more likely to occur if one or both parents are dwarfs but it isn’t the passing of the abnormal gene, which occurs in most genetic disorders, that is the mechanism. Complicated genetics but the bottom line is that dwarf parents can have a normal child and normal parents can have a dwarf child.
            Giganticism is not a genetic disorder but rather an endocrine disease. It is most often caused by a pituitary tumor, which produces excess growth hormone (GH). This excess GH causes the victim to grow very tall. If the tumor appears before the bone growth plates close. If the tumor appears afterward, the person cannot grow taller but rather will develop Acromegaly---a condition where the bones thicken—particularly over the eyes and the jaw, as well as the hands and feet. If the tumor appears early and is not treated for many years after the growth plates close, the victim will suffer a combination of Giganticism and Acromegaly. He will be both tall and thick boned. Like the wrestler Andre The Giant. But this is not a genetic disorder so the probability that a family with dwarfism would also have a Giant is no more likely than anyone else having a child with Giganticism.
               So, yes, your family could have both a dwarf and a giant child but the probability of this occurring would be extremely small statistically.
            The use of pituitary extracts for short stature is to supply excess GH to the victim. If his short stature is caused by a GH deficiency then the extract will help. But it will not help someone with achondroplastic dwarfism.

5-16-07: Gas As Tool for Murder

Q:            In my scenario the villain has some wine with the heroine and slips her a drug to make her very, very sleepy – incapacitated but still breathing. There are lots of candles burning in the room, or perhaps an oil lamp, as the heroine likes soft light. When she has fallen asleep, the villain opens the tap of the gas cylinder behind the gas fireplace so that gas starts to leak into the room. The heroine does not wake up as she is in too deep a sleep. What exactly would kill the heroine: would it be gas inhalation/oxygen starvation or would it be more likely that there would be an explosion and/or fire caused by the gas and the candles or oil lamp?
Diane Korber, Cape Town, South Africa.

A:            Definitely an explosion. Any open flame, including pilot lights on ovens, water heaters, or central heating units would ignite the gas once it accumulated to any degree. So could flipping on a light switch or striking a match. So, under the circumstances you describe, the room would explode long before enough gas accumulated to render the victim unconscious.
            Natural gas is classified as a suffocating gas. It is not a toxic gas as is cyanide or chlorine since it doesn’t react with the blood or the cells of the body. It causes problems when it accumulates in a sufficient quantity to reduce the amount of oxygen (O2) in the air, thus suffocating anyone who breathes the gas-laden air. Normal room air contains 21% O2. If the O2 level falls to 15 to 18% the victim would become short of breath, sleepy, and develop headaches. If lower, the victim would become confused and lethargic and as the level of O2 continued to fall, he would lapse into a coma and die from asphyxia. To render the victim unconscious, enough gas would have to accumulate to cause the concentration of O2 within the room to fall below 10-15% or so. For example, if enough gas entered the room to replace half the room air, the air in the room would then be half air and half gas. In this situation, the O2 content of the air in the room would also fall by 50%. This means that the O2 percentage would fall from 21% to about 10.5%. This would be a deadly situation.
            For the gas to accumulate, the room would need to be sealed or at least be poorly ventilated. The rate of accumulation would depend upon the size of the room, the rate at which the gas entered, and the degree of ventilation. It’s highly variable. But, an open flame and a room full of gas are not compatible. The room would explode long before the level of O2 fell enough to do the victim in. So, if you want the victim to die from asphyxia rather than an explosion, dump the candles and the oil lamp.

5-15-07: GSW to the Aorta

Q:            I'm a fan of the classic British crime drama THE PROFESSIONALS. In the show a main character is shot once through the back and once through the chest with the bullet lodging in the aorta. Luckily, it is 1970s TV, and he recovers within twenty minutes with no adverse affects. My question(s): Is it likely he would survive these injuries? If he did survive, what would recovery time be like--and what would the residual lasting effects be of such an injury? Would a return to active duty be likely?
Diana Killian
Author of The Poetic Death series & The Corpse Pose series
http://www.girl-detective.net

A:            A gunshot wound (GSW) to the aorta is almost uniformly fatal. The aorta is the major artery in the chest that sits above the heart. All the blood must pass through it on its journey from the heart to the far reaches of the body. Any defect in the aorta, whether from a GSW, a knife, an auto accident, or any other significant trauma, allows blood to escape. And since the blood in the aorta and the other arteries is under pressure, it does so rapidly. Add to this the fact that blood that escapes the thoracic aorta (the chest portion of this vessel that extends from the heart to the legs) will fill the chest and compress the lungs or the pericardium (sac that surrounds the heart) and compress the heart. In this situation, death comes very quickly.
            Can people survive a GSW to the aorta? Sure. I’ve seen it. It’s just not the most likely outcome. And, as in the story you mention, there is no way the victim would “recover in 20 minutes.” If he is to survive he would need emergent surgery to repair the aorta. And this would mean he would have to survive long enough to get the hospital and into surgery. This is extremely unlikely and that’s why we rarely see it. In 35 years I’ve seen it twice---once a GSW and once an ice pick.
            If he did survive to get to and get out of surgery and if all went well, he would remain in the hospital for a week or so, recover at home for many weeks, and after a few months could return to normal and go on with life. Of course there are all sorts of complications that can rise up along the way and these would kill him or render him disabled for many months if not forever.

5-14-07: Using DNA to Determine Who Shed Blood at a Crime Scene

Q:            If the police found blood at a crime scene, but no bodies, and the police can't find the woman who lives there or her ex-husband--how much could they tell by testing her son's DNA? Could they tell that the blood belonged to one parent (as opposed to a sibling with similar DNA)? And could they tell if it was the mother's or father's side?
Donna Andrews
http://donnaandrews.com

A:            DNA from the blood found at the scene could be used to determine that the blood came from the missing mother in several ways. The most straightforward method would be to obtain DNA that was known to be that of the mother from another source. Maybe from her toothbrush or from an envelope or stamp that she had licked. A match would prove that the blood came form the missing mother. In addition, DNA can in some cases be obtained from a simple fingerprint. As the print is laid down, oil and cells from the skin are deposited. DNA can be gleaned from the cells in the print and used for matching. This way, if both the print and the DNA matched that of the missing woman, there would be no doubt as to who left the blood at the scene.
            Also, the ME could use the missing woman’s hair obtained from her hairbrush. Hair is often removed with the bulb intact during brushing. Nuclear DNA obtained from the cells of the bulbs could be matched to the blood and if they were identical, the hair and the blood came from the same person. But, if no bulbs were present, all is not lost. Mitochondrial DNA (mtDNA) can be obtained from the hair shaft and if this matched the mtDNA from the blood, it would be strong evidence that the blood was that of the same person that left the hair on the brush. Not absolute proof, but strongly suggestive.
            The DNA used for standard DNA testing is nuclear DNA and it can be extracted from any nucleated cell. But, cells also contain non-nuclear DNA. This DNA is found within the mitochondria, which are small organelles that reside within the cytoplasm of the cell and serve as the cell’s energy production center. A small amount of DNA is found within the mitochondria, but each cell has many mitochondria.
            Mitochondrial DNA has several characteristics that make it unique. It is passed from generation to generation by the maternal linage, mutates rarely, is found in places where nuclear DNA doesn’t exist, and is exceptionally hardy.
            Your mtDNA is inherited unchanged from your mother and only from your mother. And she received hers from her mother, and her mother from her mother, and so on. Why is this? At fertilization, the egg supplies the cell and half the DNA while the sperm supplies only half the DNA. The sperm cell itself breaks down and disappears after passing its genetic material into the nucleus of the egg cell. This means that the actual cell and all the cell components (including the mitochondria) of the developing zygote come from the mother. As the cell divides and multiplies, these mitochondria are copied and passed on, generation after generation. This means that all the cells of the body contain identical mtDNA.
            If mtDNA from the blood and from the son matched, this would prove that the blood came from a sibling or a maternal relative of the boy. It could be his mother, his sister or brother, his maternal grandmother, or his maternal aunt, since each of these individuals shares the same maternal lineage and thus the same mtDNA. This is not as strong a match as standard DNA, but in your scenario, it would be adequate to identify who shed the blood at the scene.
            Lastly, the son and the mother would share much DNA in common, but this would not be absolute evidence that the blood at the scene was from the boy’s mother. Only that it was likely from a close relative. In paternity testing, the ME must have blood from both parents and from the offspring to prove or disprove paternity. The child receives his DNA from both of his parents, half from each, so his DNA is a mixture of his parents DNA. For this reason, DNA from both parents are needed to prove paternity. The same holds true for your scenario. If the ME had blood from the boy, from the scene, and from the boy’s father, then a paternity-like analysis would prove that the blood at the scene came from the boy’s mother. In your scenario, since the boy’s father is also missing, the ME would need to locate DNA from the father in a similar fashion as described above. If he then had DNA from a hairbrush, toothbrush, stamp, etc. that was known to be from the father, he could prove the blood at the scene came from the mother.

5-9-07: Car Versus Pedestrian Accident

Q:            In my book, a fifteen-year-old male football player was hit by a drunk driver. He lands on the hood, slides up the windshield, and then the driver slams on the brakes and the boy slides back down off the car onto the ground. What type of injuries would he sustain? Are broken legs and/or broken ribs (with a possible punctured lung) plausible?
Anne M.
http://www.allanne.com

A:            Yes, this could easily happen and indeed often does. The boy could suffer all types of injuries in any combination and in any degree of severity. Or he could suffer only a few minor scrapes and contusions. There is an adage in medicine that says: whatever happens, happens. It’s all possible.

Head: He could suffer a concussion (loss of consciousness with no real brain injury), a brain contusion (brain bruise), a skull fracture, severe brain trauma and death, bleeding into or around the brain, or a severe neck injury that could also be lethal. And any combination of these.

Chest: Rib fractures with or without a pneumothorax (punctured lung), a lung or cardiac contusion (bruise), a sternal (breastbone) fracture, or only minor chest bruises and scrapes.

Abdomen: Superficial contusions and scrapes, rupture of the liver, spleen, kidneys, bladder, or bowels, or rupture of a major blood vessel with fairly quick death.

Extremities: fractures of almost any type, severity, and combination. A common fracture in car versus pedestrian accidents are fractures of the leg bones in and around the knees. This is where the bumper usually strikes the legs. There could be fractures of the upper leg (femur), knee )patella), or lower leg (tibia—larger bone or fibula—smaller bone), or any combination of these.

5-4-07: GSW versus Stiletto Heel Wound

Q.            My male victim was found bound, wearing only a pair of pantyhose in a field of wheat stubble with two holes in his chest. The immediate assumption is to be that they are GSW's. I want the weapon to actually be something more unusual like a stiletto heel. Would the ME of a city the size of Topeka (approx. 50K) be likely to mistake the wounds during the primary examination in the field?
Tony H, Topeka, KS

A:            Yes, this could happen. In the field, he would see two round wounds in the victim’s chest and could only speculate as to what caused them. Since GSWs are common and the old medical adage says “Common Things Occur Commonly,” he would likely think these were either GSWs or perhaps some other round stabbing device. He would never think of spike heels---unless a bloody one was lying nearby. Also, the coroner wouldn’t likely visit the scene. He could, but more likely one of the coroner’s techs would. And they would be even more likely to make the assumption you outline.
            Once the coroner got the corpse to the morgue and began his autopsy he would figure it out very quickly. Maybe not the exact weapon used, but he would know it wasn’t a GSW. The X-rays that are taken as part of the autopsy would show no bullets or bullet fragments, and since there would be no exit wounds, he would know that a GSW was not the cause of the injury.
            How could he figure out that it was a stiletto heel? Perhaps some of the leather or whatever material the shoe was made of chipped off during the attack and he found the small fragment in the wound. Analysis if this might lead him the conclusion that the weapon was a shoe heel. And if the shoe was an uncommon type, the material and color and chemical analysis of the chip might even reveal the shoe’s manufacturer.

4-27-07: Poison That Mimics a Natural Death

Q:            I am working on a short story in which a person is poisoned. However, I'm not sure what type of poison I should use. The requirements are: 1. A fast acting poison. 2. The cause of death should appear natural (i.e. heart failure, or some other illness) 3. Symptoms of death would seem natural under a normal Medical Examination
             Is there such a substance? Would it be readily available to the general public (without prescription or having to sign a form that would leave a trail to the killer)?
Vaughn C. Hardacker

A:            I get this question a lot. Seems to be a common plot. The problem is that most drugs don’t kill quickly and on demand. And those that cause a dramatic death like a heart attack are usually easily found at autopsy. In fact, there is no substance that can't be found if the ME looks for it or does an aggressive toxicological evaluation. The combination of gas chromatography and mass spectroscopy (GC/MS) will give the exact and individual "fingerprint" of virtually any and all chemicals.
            The trick is to make the death look like a heart attack or some other medical condition so the ME will not perform an autopsy. These could happen if your character is older and has a history of heart disease. Here the victim's private MD might sign the death certificate with the cause of death as a heart attack (myocardial infarction or MI) and the ME might accept that as the true cause of death and not get involved. He can or cannot get involved solely at his discretion. Here you could use cyanide, which causes a sudden and dramatic death, or any other poison since if no autopsy were done it wouldn’t be discovered.
            Other reasons the ME might not get involved are such things as he could be lazy or corrupt or in on the murder or gets paid off. Also if your story takes place in a small town where there is no ME but rather a locally elected coroner who could be the local mortician or dog catcher, he wouldn't be as likely to do an autopsy and for sure all the toxicological stuff. He simply might not know how to handle a poisoning death and also these tests cost a good deal and his budget might be small. He wouldn’t be inclined to bust his budget on one case.
            On the other hand, there are several drugs that can actually cause a MI. Not with any degree of certainty—they may or may not do the victim in---but it’s possible. Large doses of cocaine and amphetamines can cause a rapid rise in blood pressure and a spasm (narrowing) of the coronary arteries (these are the ones that supply blood to the heart muscle) and this can lead to a MI or a deadly change in the heart’s rhythm---either of which could lead to a sudden death. But, whether this works in a particular person or not, is unpredictable. If your character is older or has known heart disease and if you your villain slipped some cocaine or amphetamines into his drink, he could collapse and die and the ME might just right it off as an MI and never do an autopsy. I wouldn’t use cocaine here since it has such a bitter taste and would numb the victim’s mouth and throat and he would know something was wrong. But if the ME did do an autopsy, the normal drug screen that is done as part of this procedure would easily detect both amphetamines and cocaine.
            Another choice, as I mentioned above, would be cyanide. It is a “metabolic poison” that basically shuts down the ability of cells to use oxygen. The red blood cells cannot carry oxygen to the tissues and the tissue cells of the body can’t use the oxygen anyway. It is as if all the oxygen were removed from the body instantly. This process is immediate and profound and leads to death in 1 to 10 minutes, depending on the dosage.
            Symptoms are rapid breathing, shortness of breath, dizziness, flushing, nausea, vomiting, and loss of consciousness, maybe seizure activity, and finally death. The victim would develop sudden, severe shortness of breath, a flushed face, perhaps clutch at his chest, collapse to the floor, and die, with or without having a seizure in the process. It would look like a heart attack.
            The problem is that cyanide combines with the hemoglobin of the blood’s Red Blood Cells (RBCs) to form cyanohemoglobin, which imparts a bright cherry red color to the blood and tissues. If the victim cut or scraped himself as he fell, his blood would be noticeably red. And at autopsy, the ME would see that the blood and the tissues were reddish and any lividity that had developed in the corpse would be pinkish rather than the usual bluish-purple and he would likely suspect cyanide. Testing would then follow.
            Another situation would be if your victim had heart disease and was taking certain cardiac medications. An over dose or adverse reaction or a deadly combination of these could be written off as accidental. Even if the ME found the drugs in excess levels at autopsy he might simple assume the victim got his meds mixed up or miss used them. Happens all the time. Some examples would be:
Digitalis: If he were taking digitalis for heart failure or a cardiac arrhythmia he would likely be taking one 0.25 milligram (mg) pill each day. If someone slipped an extra pill or two into his food each day for a week or two, the level of digitalis in the blood would rise and could reach levels where he suffered a deadly cardiac arrhythmia (change in the normal beating of the heart, and collapse and die. This is a common effect of digitalis excess and unfortunately this happens from time to time in people taking this medication. The ME would assume he had simply gotten mixed up and took too much of his digitalis. You would be surprised how many people believe that if one pill of their medication is good two must be better. Or your killer could crush up 8 or 10 Digitalis tablets and put them into some food and feed it to the victim. This would cause an acute elevation of the digitalis level and all the things described above.
            Or your character could have coronary artery disease with angina and could be using a long-acting nitrate such as Imdur (a pill) or one of the many nitroglycerine patches---Minitran and Transderm Nitro are two common ones. The taking of one of the Erectile Dysfunction (ED) drugs—Viagra, Cialis, or Levitra—while using a long acting nitrate can be treacherous. Both nitrates and Viagra and its friends dilate (open up) blood vessels throughput the body. That’s how they work. But too much of either class of drug or the two classes of drugs taken in combination can cause excess dilatation and this can result in a profound drop of the person’s blood pressure (BP). This in turn can cause a MI or a cardiac arrest. With Viagra, this would most likely happen about 45 minutes to an hour after ingestion and with the other two you could stretch that out to 3 or 4 hours or so. This reaction is unpredictable but does happen and can lead to the type of death you want for your story.
            Here the ME would assume the victim used Viagra in the face of the long-acting nitrates and had a bad reaction. Again, happens all the time.
            Another option is that your character could be depressed and could be taking a class of antidepressant medications known as Monoamine Oxidase Inhibitors or MAOIs for short. If so, he would be vulnerable to the action of some other drugs and foods.
            MAOIs alter the chemistry of the brain by blocking the enzyme monoamine oxidase, which normally breaks down norepinephrine and other neurotransmitters in the brain. Complex biochemistry and it’s not necessary to explain it. Just that a person on a MAOI must not take some other meds and must avoid certain foods. If not a Hypertensive Crises could ensue. In this situation the BP abruptly shoots up and the person can suffer a stroke, heart attack, and death. This reaction can happen anywhere from 30 minutes to 3 or 4 hours after ingestion of the conflicting medication. Again, this reaction is unpredictable and might or might not happen in any given individual. But it can and does happen, so it will work in your story.
            Common MAOIs are: Nardil, Pamate, and Marplan.
            Drugs that can cause a Hypertensive Reaction when taken in conjunction with one if these MAOIs are:

Amphetamines
Diet Pills of all types
Many High Blood Pressure meds
Flexeril (Cyclobenzaprine)
Prozac (Fluoxetine)
Paxil (Paroxetine)
Zoloft (Sertraline)
Demerol (Meperidine)
Any Tricyclate Antidepressant. These include: Elavil (amitriptyline), Sinequan (doxepin), and Tofranil (imipramine)—and many others.
The list is very long but the above are a few common ones.

            Foods to avoid are those that are high in the amino acid tyramine such as: certain cheeses, fava beans, smoked or pickled meats, fermented sausages (bologna, pepperoni, salami, and summer sausage), alcohol, and caffeinated drinks such as coffee, tea, colas, and chocolate. The list is much longer but this gives you the idea and some choices.
            If your character was secretly given or was taking one of the MAOIs for some mild depression, your villain could then slip him a few amphetamines or diet pills or a couple of Paxils and wait. In a few minutes to several hours his BP would shoot up, he would develop a severe headache, blurred vision, shortness of breath, and then collapse. He could or could not have a seizure with this. The elevated BP damages the brain and might even cause bleeding into the brain. This would be called a hypertensive hemorrhagic stroke. That means that the stroke resulted from bleeding (hemorrhagic) into the brain due to an elevated BP (hypertensive).
            As you can see, using a drug to mimic a heart attack and getting away with it takes a bit of clever slight of hand. But that’s what storytelling is.

4-25-07: Identifying Skeletal Remains

Q:            In my story, a murderer kills multiple people, dumps them (but does not bury them) in a somewhat dilapidated abandoned barn in Iowa, and sets fire to the bodies and the barn using accelerants. The site is allowed to burn down, and left unexamined for five years. Considering the climate and wild animals, what could investigators expect to find if they examined the site now? Would there still be anything recognizable? Anything useful for identification? The fire burns the bodies VERY badly.
DKF, Indiana

A:            The odds are that only skeletal remains would be found. What the fire didn’t destroy, putrefaction would. So, there would be no tissues left and thus no fingerprints or tissue DNA. This would make identification of the remains difficult and perhaps impossible. And if predators entered the picture and hauled away many of the bones, he might have only a few left to analyze. But, the ME does have a few tricks.
            He would call in a forensic anthropologist to determine the height and stature, the sex, approximate age, and perhaps the race of each of the victims. He could then compare this to any missing persons list he had and perhaps come up with the IDs. Also, clothing or jewelry at the scene might have survived the fire and these too could help.
            The same goes for any teeth found. Even if only a few are found, they could be compared to the dental records of any suspect missing persons and the IDs might come from that. At least some of them. Or none of them.
            The anthropologist might also be able to determine the approximate time of death and the cause of death. Skull and bone fractures from blunt trauma or chipped and shattered bones from knife blades or bullets might help in this regard. And blade or bullet fragments might be found. If the bullet could be matched to a particular gun, this could lead to the killer and in turn to the victim’s ID.
            DNA would not likely survive such an intense fire, but drilling into the pulp of the teeth might yield usable DNA. Or not. It could go wither way. Of course, the ME would need DNA from a known missing person to compare it with or the DNA would be worthless. This could be from a suspect missing person’s tooth or hair brush or from licked letters and stamps from the suspected person.
            The identification of skeletal remains is a difficult and complex art. This is a brief sketch of some of the things that the ME and the anthropologist would do. And it might be all you need for your story. If not or if you want to know more, my book Forensics For Dummies covers this subject in greater detail.

4-20-07: DNA in Half-siblings

Q:            A woman is murdered. At the scene of the crime, the police find a blood sample of the killer. We know the killer and the woman are half-siblings. Is this something the police would automatically and inevitably discover?
Private Ellgee, Portland, ME

A:            Not likely, but maybe. The victim and the killer could have two different blood types and their DNA could be very different, since they only share one parent in common. And if so, the ME would never consider that they were related. Unless good police work turned up that possibility.
            However, the DNA profile of the two samples could be somewhat similar and this could lead the ME to investigate further. DNA inheritance is a bit like roulette—you never know exactly what you’ll get from each parent. But even if the two DNA samples were somewhat similar, the ME could not prove their sibling relationship with nuclear DNA alone. He could only suggest the possibility.
            But, if the ME were suspicious, he has another tool in his arsenal. If the common parent were the mother, then the two would share the same mitochondrial DNA (mtDNA). This DNA is passed down through the maternal line exclusively. So if the two samples had the same mtDNA, the ME would know that the victim and the killer were maternally related. They could be brother and sister (same mother), or cousins (same grandmother through the maternal side). But he would not do this expensive and time-consuming testing unless he was suspicious in the first place. If the common parent were the father, then mtDNA would be of no value since they would have had different mothers and thus different mtDNA.
            If you want to pursue thus line of investigation in your story, you can find a full discussion of DNA technology, including mtDNA, in my book Forensics For Dummies.

4-19-07: Insulin to Sedate

Q:            I have a character in my story who is a Type 1 insulin dependent diabetic and I wish to know if a certain scenario is possible or plausible.
             The bad guy forces this character to inject all of the insulin left in her pen into her body, which will hopefully render her unconscious long enough for him to take her to his hideout. Is it possible that the hero could reach her before serious, irreversible damage has occurred?
             What effects, both visible and invisible, would occur after this large dose of insulin was administered? How long would it take for her to lose consciousness? How should the hero treat this character when he first arrives on the scene? Another point is that the bad guy doesn't want her to die, so is there something that he could do to stop the damage? And finally, would the victim require hospitalization, and if so, for how long?
M McGoldrick, Scotland

A:            Insulin will not work for your scenario.
            The brain requires a continuous supply of blood and nutrients, predominantly in the form of sugar. Excess insulin causes a profound and rapid drop in blood sugar levels. This causes the brain to malfunction. First the victim will become sleepy, then slip into a coma, and finally die from brain damage. The rapidity with which the victim goes through the stages will depend upon the amount of insulin given and the route by which it is administered. The brain does not live long without the steady sugar supply. So, your victim would indeed lose consciousness very quickly. In less than a minute if the insulin is given intravenously (IV), in 2 to 5 minutes if given intramuscularly (IM), and in 10 to 15 minutes if given subcutaneously (Sub-Q), which is an injection just beneath the skin.
            But, the loss of consciousness signals the onset of brain damage and every minute that passes, the damage worsens. How long does it take for the damage to be severe and permanent? It is highly variable and depends upon the amount of insulin given and the degree to which the blood sugar level is depressed. It could be permanent in as little as 5 minutes or could take up to an hour. So, this is not a safe way to sedate someone. I’d suggest using a narcotic such as morphine or heroin, or a sedative such as Valium or Xanax along with a little alcohol, or Chloral Hydrate with alcohol (the original Mickey Finn), or one of the date rape drugs. There is an article on these latter drugs on this site under Articles. One of these should work well for your needs since they not only sedate, they prevent the victim from remembering.

4-19-07: GSW to Leg and Shoulder

Q:            My protagonist is a healthy male in his mid-thirties who is shot in the shoulder and leg from behind with a 9 mm handgun. Will he feel impact and pain simultaneously or sequentially, e.g., jolt, then searing pain? If the bullet goes through the shoulder and exits, will bleeding be light, heavy, or something in between? If the femoral artery in the leg is hit, how quickly could he bleed to death if no tourniquet is applied (he'll be thinking he has only so much time to stanch the bleeding).
S.A. Clarke, Silver Spring, MD

4-17-07: Carotid Artery Compression

Q:            Just a quick question: How long does it take for someone to die if their carotid artery is compressed?
Carola Dunn, Author of Gunpowder Plot and Fall of a Philanderer

A:            The two carotid arteries lie in the front of the neck on either side of the trachea (windpipe) and carry blood from the heart to the brain. They supply 90% or so of the brain's blood, with the rest coming form two small vertebral arteries that travel along the spine and over the back-most portion of the brain. The carotids are interconnected in the brain so that in a normal individual compressing a single carotid artery will have little effect. Compressing both can cause a loss of consciousness in 15 to 20 seconds and death in 2 to 4 minutes.
    One general rule in medicine is that if the heart stops, the victim will lose consciousness in about 4 seconds if standing, 8 if sitting, and 12 if lying down. This simply reflects the effects of gravity on blood flow. These numbers would also mostly hold true if both carotids were suddenly pressed shut---not easy to do---see below.  But, to the brain, the complete interruption of blood flow through carotids would look the same as it would if the heart had stopped. Either way, the brain would receive no blood supply. And the brain needs a continuous supply of blood to function and survive.
    Another medical truism is that dizziness, loss of consciousness, and sudden death are simply gradations along the same scale. That is, what makes you dizzy can make you lose consciousness, and what makes you lose consciousness can cause death. One of the things that can do this is compression of the carotid arteries. Brief compression, can cause dizziness, longer compression can cause loss of consciousness, and even a longer period of compression can cause death.
    Another variable is how severely the arteries are compressed. If only partially collapsed, the victim might have no problems. Severe and almost complete compression can cause loss of consciousness and death in short order. And anywhere in between. Significant and potentially deadly compression can result from strangulation--either manual or ligature, hanging, or an aggressively applied choke hold.
    So, depending upon the nature, force, and duration of the compression, your victim could have no symptoms, become dizzy, lose consciousness, or die. Or could progressively move form one of these to the next. The time require for death could be a couple of minutes or many minutes if the compression is less severe or intermittent. As the victim struggled, he could intermittently release the choke hold and this would prolong the ordeal.
    All these variable means that you can have it almost anyway you want. The killer could overpower the victim, render him unconscious in 20 seconds, and kill him in 2 minutes. Or the struggle could go on for many, many minutes. It's up to you.

4-16-07: Determining Bullet Caliber

Q:            I have a mystery in progress and, in the interest of accuracy, would appreciate answers to a few questions. The victim died of a gunshot wound, and the projectile was still in the body. Is it possible to determine from the projectile the type of firearm used, e.g., shotgun or handgun? In my story, the weapon used is a 9 mm handgun. Is it also possible to tell, from the projectile, that it was a 9 mm? Finally, the city in which the crime occurs has its own crime lab. Can you give me an idea of a reasonable time frame for making these determinations?
S. L. Smith, St. Paul, MN

A:            If the bullet is fairly well intact, determining the caliber is usually easy and can be done shortly after it is removed at autopsy. Measuring and weighing will give the caliber. If the bullet is severely deformed, measuring is difficult and weighing alone might not give the exact caliber. But here the difference between a .22 and .45 is easy but distinguishing a .38 from a 9 mm might not be possible, since bullets of this caliber are fairly close in size. If the bullet is fragmented and only parts of it are available, the determination of caliber becomes more difficult and sometimes can’t be done at all.
            A shotgun fires a mass of small pellets so it is easily distinguishable from a handgun, which fires a single projectile.

4-12-07: GSW Treatment

Q:            Question: for my sequel to Chasin’ the Wind, my character receives a gunshot wound to his left side. It is not life threatening and treated at the ER. He is kept overnight and released. Would the wound be stitched or stapled, or is there something else the ER would use to seal it?
Michael Haskins, Key West, Fl
Author of Chasin’ the Wind
www.michaelhaskins.net

A:            Gunshot wounds (GSWs) are not usually sutured as are clean cuts. GSWs tend to be more ragged. If the bullet merely grazed the victim’s side, creating a furrow of skin and tissue loss, the wound would be cleaned and dressed and the victim would be placed on antibiotics. The wound would be cleaned and re-dressed once or twice a day. It would heal in a couple of weeks unless and secondary infection set in.
            The same is true if the bullet enters the skin and tissue and the exits out a separate wound. This is called a through and through GSW. The treatment is as above expect that a drain—basically a rubber tube---might be placed into the wound to drain away any oozing blood and tissue fluid as these can serve as a good broth for infection. The tube would be left in place for 3 or 4 days and then removed and the healing process would progress from there.

4-9-07: Treatment of Lung and Leg Injuries in a Remote Area

Q:            My story takes place in a small mountain town. A doctor is asked to ride in the copter in place of an absent paramedic to attend car wreck. Patient has a punctured lung from a broken rib. I need to know the procedure Dr. would go through on arrival and the jargon used. In same accident, child has severely crushed leg. I need to know procedure taken in the field and jargon used.
Bobby J. Shoemaker, Banner Elk, NC

A:             In the field, and particularly when helicopter transport is involved, there are only a handful of things he could do. For the punctured lung he would place the victim on an oxygen mask and start an IV and transport him to the ER. In virtually all cases a punctured lung with collapse (called a pneumothorax or pneumo for short) is not life-threatening. We have two lungs, but only need one to live. The only real complication that could endanger his life would be the development of what is called a Tension Pneumothorax. The physiology is complicated but the net effect is that pressure begins to build inside the chest and this can collapse the other lung and the heart and cause shock and death. The signs that this is occurring would be increasing shortness of breath, a fall in blood pressure, and a movement of the trachea away from the side of the injury. The trachea—wind pipe---is in the front of the neck and is easily felt. It normally sits dead center. If the injured lung is on the right side and if a tension pneumo develops, the trachea would be shifted to the left.
            Here he would insert a large-bore needle into the chest on the side of the injury. This could relieve the pressure and the victim would be fine. At the ER a thoracostomy tube (called a chest tube) would be placed to re-inflate the lung. This is a plastic tube that is passed through the chest wall and into the chest but outside the lung. It is attached to a suction device and this causes the lung to re-expand. It may take a few days for the lung to heal and then the tube is removed.
            The injured leg would be placed in an air-filled cast, strapped to a board, and the child would be flown to the ER, where surgery would be needed. Any bleeding would be controlled with applying pressure and this victim would also have an IV placed and be given oxygen via a mask. He would apply a tourniquet to the leg only if the bleeding couldn’t be controlled with direct pressure.
            The IV would be something like D5 RL—stands for 5% Dextrose in Lactated Ringer’s solution—and the oxygen would be given at 10 liters per minute.

4-4-07: Rape Report

Q:            I have a scene where my protagonist prosecutor is reading an autopsy of a woman who had been raped. What are some phrases that would be in that report?
Linda Bell Harrell, Cedar Key, FL

A:            First of all the term rape would not appear in the report since rape is a legal term and not a medical term. Only and judge or jury can determine if a rape has occurred. What the ME will do at autopsy is to look for signs of force, or penetration, and of sexual intercourse.
            Force could be in the form of drugs or restraints. The forensic toxicologist would test for drugs in the victim and then determine if the drugs present and the amounts found would be enough to make the patient complaint or unconscious. Not always easy and is often a judgment call. Restraint could be in the form of ropes or the attackers hands. The ME would look for bruises of the arms, wrist, and throat that might indicate that the victim was strangled and/or held down. Rope abrasions around the wrists and ankles could indicate that the victim had been tied.
            The problem here is that some people practice rough sex with B&D and other sex games involved. All the ME could say is that the victim was likely held down or tied up. It would be up to the jury to determine is this was consented to or not. Cuts from knives or bruises from punches would favor non-consent, but not always.
            The next thing he would look for are signs of vaginal or anal penetration. He would look for contusions and abrasions. Again, these could be for forcible penetration or from consensual rough sex. A judgment call that would be ultimately decided by the judge and jury.
            Lastly, he would look for signs of sexual intercourse. Basically, this is finding semen in the vagina, anus, or on the corpse. If semen is found, it proves that ejaculation has occurred. But rapes can occur with ejaculation and in this case, no semen would be found. But, if it is, it can also help the ME estimate the time since intercourse and this can help clear some suspects and point the finger at others.
            In living victims, the duration of sperm motility is from 4 to 6 hours. If motile sperm are found in vaginal swabs, the sexual act likely occurred less than 6 hours earlier. After that, the sperm die and begin to breakdown and fragment, and timing becomes a guessing game. First the tails are lost, leaving behind sperm heads, and then the heads and tails undergo fragmentation and destruction. The survival of sperm heads and sperm remnants in various body orifices is extremely variable so that no truly accurate timeline can be established. In general, these remnants may remain in the vagina for up to 6 or 7 days, the rectum for 2 to 3 days, and the mouth less than 24 hours.
            In cases of rape-homicide, sperm may remain in the vagina of the corpse for up to 2 weeks. So, if the ME found sperm or sperm remnants in the corpse he could say that the rape/intercourse occurred within the past two weeks. Again, this is a best guess situation.
            In his report and court testimony, your ME would simply describe the bruises and abrasions he saw on the victim’s arms, wrists, neck, etc., any injuries to the vagina or anus, and whether any semen was found or not. Based on these he might conclude that the victim was restrained, was penetrated, and that intercourse had taken place. The jury would then decide what this meant in terms of rape versus consensual sex.

4-4-07: Poisons in Five-Year-Old Skeleton

Q:            I use your Dummies book---incredibly helpful---but I have a couple of questions, if you have time to answer them. Can poisons be detected in bones of a 17-year old male that were buried in the sandy desert for five years before discovery? Or should I make the skeleton be buried longer since I want only the bones to be found, no flesh.
             You say that bones contain moisture, fat and protein how long does it take for these elements have disappeared from the bones, if at all? Would there be any dried blood clinging to the bones, or in the sand and if so, could that be used to test for poison?
J. Amadio
http://www.ghostwritingpro.com

A:            A corpse buried in a desert can either putrefy (decay) or mummify. The key is the average temperature and the moisture content of the area. In hot and dry climates, mummification is more likely. In warm and damp areas or if the body is buried during the rainy season that many deserts experience, then the corpse would more likely decay. The bacteria that cause putrefaction thrive in warm, moist environments.
            The rate of tissue destruction also increases the warmer and damper the climate. A corpse in a swamp in Louisiana could be completely skeletonized in a 3 or 4 weeks, while one in a snow bank in Minnesota wouldn’t decay until spring and might take years to be reduced to a skeleton. It is extremely variable but after five years most corpses would be skeletonized under average temperate conditions. So, within the above parameters of environmental conditions, your corpse could easily be only a skeleton or could be a mummy. Either way would work.
            If the corpse in your story were to mummify, the ME and toxicologist would have tissues to work with and a much better chance of finding any toxins that might be present. If the corpse is reduced to only bones, then there would be no tissues. And if there were no tissues there would not likely be any blood remnants, since blood is considered a tissue and is subject to putrefaction just as are muscles, skin, and organs. The same is true for the bone marrow, which is where the fats and moisture of the bones predominantly reside. Very few toxins can be found in bones, but there are several that can be found in hair. Often skeletonized remains will have hair nearby as hair is sturdier than tissues. Heavy metals such as arsenic, lead, and mercury can usually be uncovered in hair.
            What happens in your story depends upon the condition of the corpse and exactly which poison is involved.

4-2-07: Anthrax Vaccine and Treatment

Q:            Your article on Anthrax was very helpful, but my question is: If someone has been inoculated, how much of a threat is being around the powdered version? We've run across terrorists who have lots of the stuff, but it's sealed in containers ready to be smuggled. The bad guy, who has been inoculated, has a small vial of anthrax powder and forces two of my characters to inhale the stuff (a teaspoon full each) while he wears a mask and gloves. The clock is ticking and the good guys have 24 hours to be treated if I understand the process correctly?
Philip Donlay, Author of Category 5 and  Code Black
http://www.philipdonlay.com

A:            Anthrax vaccine is a series of 6 doses. The first three are given at 2-week intervals, then at 6, 12, and 18 months. After this, an annual booster is needed to maintain protection. Once completed, it protects against both the cutaneous (skin) variety and the inhaled type. If your guy was adequately vaccinated, he wouldn’t need treatment. If not, treatment should be as soon as possible with ciprofloxacin, doxycycline, or penicillin. Since inhalation anthrax is rare there are no clinical studies on the effects of treatment delay but every hour counts as the inhaled spores invade the bloodstream and spread throughout the body. If you need 24 hours, then it will work. In real life, sooner would be better. But then again, you deal with what you have. Even if treatment is delayed for 24 hours, your guy could recover completely. Or not. It could go either way so make it come out as you need.

4-2-07: Cyanide Poisoning Signs

Q:            I am one of 10 women who are writing a murder mystery. We would like to know if our victim is poisoned by sodium cyanide in sushi how long will the redness or ruddiness remain in his skin after his demise and the body is found and the authorities come? Also will the ME test him for this type of poisoning ie: stomach contents. He may not be discovered for a couple hours. Will his tongue be tested? Are there any other outward signs from NaCn? There will be no signs of foul play. He is found slumped over.
Mary Ann Kerns, Jackson, NJ

A:            Cyanide is a metabolic poison, which means that it poisons the cells of the body. It reacts with the iron in cytochrome oxidase, an enzyme necessary for the cell to use oxygen. This reaction prevents the body’s cells from using oxygen and they begin to die rapidly. It is as if all the oxygen was suddenly removed from the body. It’s still present, it’s just that the cells can’t use it.
            Since the cells no longer remove oxygen from the blood, the blood remains very well oxygenated (rich in oxyhemoglobin) and thus bright red. Another contributor to this cherry-red color is the reaction of cyanide with the blood’s hemoglobin to produce cyanohemoglobin, a bright red compound. This means that the blood of victim’s of cyanide exposure is bright red in color. As the blood settles and produces lividity, the lividity reflects the red color of the blood.
            At autopsy, the ME would see the bright red blood, the reddish hue of the internal organs, and pinkish lividity and would suspect the presence of cyanide (or Carbon Monoxide which also turns the blood bright red). He would then test for both. He might also detect the typical bitter almond odor of cyanide. That is, if he were capable. Curiously, the ability to detect this odor is genetically determined and about 50% of people cannot.
            So, your victim would have pinkish lividity instead of the usual bluish-purplish lividity and bright red blood and organs. Since all bodily processes cease at death, this colorization would remain until the body decayed. The ME would readily see this and test for cyanide. There would be no need to test the victim’s tongue. The blood, tissues, and stomach contents would each test positive for cyanide and the ME would know the cause of death. He might then have the toxicologist measure the cyanide level in the blood to confirm his suspicions.

4-2-07: Codeine OD

Q:            My heroine has been given Tylenol with codeine by the bad guy, ingested unknowingly in a cup of coffee. She has an adverse reaction to codeine. Would the ER doctors give her any drugs to counteract this, and if so, which ones?  Or would they simply let her sleep it off and monitor her? 
Ruth Carrillo, author of The Bard’s Circle Chronicles Series

A:            Codeine is a opiate narcotic, which means it is in the opium family. In fact, it and morphine are the two principle substances obtained from the opium poppy. As with all narcotics, it depresses many bodily functions in the user. The symptoms of codeine ingestion are giddiness, sleepiness, loss of balance and coordination, coma, and death. The drug depresses the respiratory center of the brain so that if too much is taken the victim lapses into a coma, stops breathing, and dies from asphyxia.
            However, these effects would not be considered “adverse” reactions since they are predictable and consistent. An adverse reaction would be such things as an allergic reaction. And an allergy to codeine is not an uncommon occurrence. So, I’m not exactly sure what you mean by “adverse” reaction.”
            If you mean an allergic reaction, the victim would develop hives, redness to the skin, wheezing and difficulty breathing (like an asthmatic attack), low blood pressure, and could slip into anaphylactic (allergic) shock and die. The treatment is to give an intravenous (IV) or subcutaneous (Sub-Q) injection of Epinephrine, IV steroids (such as Decadron or Solu-Medrol), and IV Benadryl. This should rapidly reverse the allergic effects. Each of these drugs might have to be given again, if the symptoms and signs of the allergic reaction reappear. The reaction should subside and after about 12 to 24 hours would be unlikely to recur.
            If you mean that the person reacts to the codeine in the more predictable manner, then the treatment is directed toward breathing for the victim and reversing the effect of the narcotic. Breathing for the victim could be done two ways. An Ambu bag attached to a facemask would be easy and immediately available in any hospital. The paramedics also carry them. An ambu bag is football-shaped, made of rubber or some synthetic material, and works like a bellows. It is attached to a facemask and each squeeze of the bag forces air through the mask, which when held tightly against the victim’s face forces air into the lungs. The second method is to place an endotracheal (ET) tube. This is a plastic tube that is passed thought the victim’s mouth or nose and into the trachea (wind pipe). Either an Ambu bag or a mechanical ventilator is then attached to the ET tube and air is rhythmically forced into the lungs. This must continue until the drug wears off.
            To hasten this process, Narcan is given IV. This is a drug that blocks the effect of the Codeine. It works in about a minute. Again, the drug might have to be given several times over the first hour or so if the victim begins to slide back into a coma. Once the effects of the drugs wear off the victim would be essentially normal. Unless brain damaged occurred during the time he wasn’t breathing, that is.

4-2-07: Cardiac Arrest From Blunt Trauma

Q:            I’ve just finished a scene in which my good guy gets hit in the chest by a bullet. He’s wearing his body armor. I’m thinking that trauma to the heart could stop it and then I’ll have the folks around him apply CPR to bring him back. Am I within the base pads?
Norm Benson, Lower Lake, CA
http://www.normbenson.com

A blow to the chest can indeed cause a deadly change in heart rhythm (cardiac arrhythmia), usually in the form of what we call Ventricular tachycardia (a rapid rhythm that is not very effective at pumping the blood) or heart block (a block in the conduction of electricity from the upper to the lower part of the heart), which is a very slow and ineffective rhythm. Both can cause shock and death if CPR isn’t instituted very quickly and then either medication (for the former) and a meds and pacemaker (for the latter). This is however an extremely rare occurrence and would not likely happen under the conditions you describe. Like virtually never. Of course anything is possible, bit that doesn’t make it plausible. It simply takes a more massive blow than could be provided buy something as small as a bullet, regardless of its speed. A 2X4 or a car bumper or a fall from a height or a concrete block, okay, but a bullet, no.